As a health-related raw material, Damiana Extract must meet strict safety benchmarks. Ensure the supplier provides a Certificate of Analysis (COA) for every batch, covering heavy metal limits (Lead, Arsenic, Mercury) and microbiological safety (E. coli, Salmonella, Mold). For entry into major markets, look for ISO 22000 or GMP (Good Manufacturing Practice) certification. If the product is intended for the US market, compliance with FDA GRAS (Generally Recognized as Safe) or DSHEA regulations is essential, while EU buyers must check REACH and Novel Food status.